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GEDI

GENE DISCOVERY/GENETIC DISORDERS

    Welcome to GEDI

The goal of the GEDI (Gene Discovery) project is to develop

a. An integrated bioinformatics environment for discovery, identification and characterization of genes and gene networks involved in complex multigene disorders


b. Tools and algorithm for interactive and automated reconstruction, annotation, validation, comparative analysis and visualization of molecular networks


c. A library of curated and automatically generated disease models produced using the GEDI system that will serve as a public repository for the constructed disease models

    GEDI Entry Points
    Search based on Gene

Search based on Entrez Gene_ID or Gene_Symbol to get their respective Gene Annotations, Associated Diseases, Protein-protein Interactions (from BIND, BioGRID, HPRD and Geneways - text mining data) Example: (Gene_ID : 8573 or Gene_Symbol : CASK)

        

Coordinates/Position (Example: chr6:13,500,001-15,500,000)

 
    Search based on Disease

Search based on either OMIM_ID or Disease Title/Disease Name (Example: OMIM_ID : 209850 or Disease Name: Autism)

        

 
    Search based on KEGG Pathways

Search based on either KEGG Pathway ID or KEGG Pathway Title (Example: path:map04340 or Hedgehog signaling pathway)

         Help

 
    Search based on Gene Sets (Gene IDs or Gene Symbols) OMIM_IDs or Interacting Pairs

[IDs seperated by newline]

Given a list of Entrez Gene_IDs or Gene_Symbols you can get their respective Gene Annotations, and given a list of omim_ids one can get their respective disease annotations (Example: Autism Gene list  Disease list  Interacting pair list)